Luteolin hmoov

Luteolin hmoov yog dab tsi?

Luteolin hmoov yog ntuj tsim flavonoid compound uas muaj nyob hauv ntau cov nroj tsuag. Nws muaj ntau yam kev ua haujlwm tshuaj, xws li tiv thaiv kev ua xua, tiv thaiv kev ua xua, txo qis uric acid, tiv thaiv qog, tiv thaiv kab mob, tiv thaiv kab mob, thiab lwm yam. , txo qis uric acid, kho kab mob plawv, thiab kho&"cov leeg nqaij atrophic txha nraub qaum."" Cable sclerosis", SARS, kab mob siab, thiab lwm yam.

Luteolin hmoov tau nthuav dav dav hauv qhov. Nws yog lub npe vim tias nws tau cais tawm los ntawm nplooj, qia, thiab ceg ntawm Resedaceae luteolin genus herb, Resedaodorata L., thiab tuaj yeem muab tau los ntawm ntau yam khoom siv kho mob ntuj, cais los ntawm zaub thiab txiv hmab txiv ntoo. Qhov kev tshawb pom tam sim no feem ntau pom muaj nyob hauv cov khoom siv tshuaj xws li honeysuckle, chrysanthemum, nepeta, Prunella vulgaris, artichoke, perilla, scutellaria, nudiflora thiab lwm yam khoom siv kho mob, nrog rau Brussels sprouts, zaub qhwv, zaub paj, beets, zaub paj, zaub paj, Celery, kua txob qab zib, kua txob, txiv ntoo hauv av thiab lwm yam zaub thiab txiv hmab txiv ntoo, lwm yam khoom cog xws li txiv roj roj thiab kua txiv liab, ntxiv rau cov tsis muaj tsiaj qus, thyme, lamiaceae tag nrho-nplooj ntsuab bluegrass, ajuveniles, thiab lwm yam kuj muaj luteolin.

Tamarindus indica pulp tsis muaj luteolin, tab sis lub husk muaj luteolin. Muaj ntawv ceeb toom txog luteolin hauv nplooj ntawm capers.

Cov Ntaub Ntawv Tseem Ceeb:

Luteolin Hmoov Cov txiaj ntsig:

1. Anti-inflammatory

Tam sim no nws ntseeg tias kev tiv thaiv kev ua haujlwm ntawm luteolin tuaj yeem tiv thaiv kev tsim cov nitric oxide (NO) thiab lwm yam kev mob cytokines xws li qog necrosis factor-α (TNF-α) thiab interleukin-6 (IL-6), thiab tiv thaiv protein Tyrosine phosphorylation muaj feem cuam tshuam nrog kev qhia noob los ntawm kev hloov pauv cov ntaub ntawv nuclear (KB-NF-KB).

2. Los tiv thaiv qog

Cov txheej txheem tiv thaiv qog nqaij hlav ntawm kev ua yog ntau thiab nyuaj. Cov kev tshawb fawb tau pom tias luteolin hmoov ntau tuaj yeem xaiv qhov txwv tsis pub muaj cov roj acid synthase kev ua haujlwm ntawm qog noj ntshav prostate thiab mob qog noj ntshav ntawm lub mis, uas cuam tshuam nrog nws cov qog tiv thaiv qog nqaij hlav loj hlob thiab apoptosis; luteolin tuaj yeem muaj txiaj ntsig Txo qhov tshwm sim ntawm kev mob qog noj ntshav hauv plab thiab qog loj los ntawm dimethylhydrazine, uas cuam tshuam nrog nws lub peev xwm los tswj lipid peroxidation, tiv thaiv oxidation, thiab tiv thaiv kev loj hlob; luteolin tuaj yeem tiv thaiv kev ntxeem tau thiab txav tau lub peev xwm ntawm qog noj ntshav qog noj ntshav HO8910PM hauv qhov koob tshuaj-nyob hauv vitro -tswj kinase 2 (ERK2)

3. Tshuaj tiv thaiv tsis haum

Luteolin tej hmoov tuaj yeem tiv thaiv kab mob immunoglobulin E (IgE) -mediated kev ua xua ua los ntawm tib neeg lub cev mast, suav nrog histamine, leukotrienes, prostaglandin D2, thiab tso tawm monocyte-macrophage colony stimulating factor. Cov txiaj ntsig tuaj yeem cuam tshuam nrog kev txwv ntawm Ca2+ kev nkag thiab cov protein kinase C (PKC) kev hloov chaw.

4. Los tiv thaiv kab mob demyelinating kab mob

Luteolin tuaj yeem tiv thaiv oligodendrocytes tiv thaiv kev puas tsuaj los ntawm hydrogen peroxide nyob rau hauv ib koob tshuaj-nyob rau hauv vitro, muaj zog tiv thaiv phagocytosis ntawm myelin los ntawm macrophages, txo qis kev tsim cov cellular reactive oxygen hom, thiab txo qhov kev qhia ntawm iNOS protein. Thaum noj tshuaj tsawg, qib NO TSIS tsim los ntawm macrophages tau txo qis.

5. Anti-fibrosis

Luteolin hmoov tuaj yeem txo qis qib ntawm daim siab fibrosis, txo cov ntsiab lus ntawm hydroxyproline (HYP), malondialdehyde (MDA) thiab kev qhia ntawm hom I procollagen mRNA hauv daim siab nqaij, thiab tuaj yeem tiv thaiv kab mob qog nqaij hlav hauv lub cev (HSC) hauv vitro Kev nthuav tawm thiab kev sib txuas collagen . Nws kuj tseem tuaj yeem txhim kho kev hloov pauv keeb kwm ntawm kev mob ntsws ntsws fibrosis los ntawm bleomycin, txo qis lub ntsws ntsuas, txo qhov nce ntawm MDA thiab HYP, thiab txwv tsis pub nthuav qhia kev hloov pauv kev loj hlob-β1 (TGF-β1) mRNA hauv lub ntsws nqaij, Hauv vitro tuaj yeem tiv thaiv kev nthuav dav ntawm tib neeg embryonic ntsws fibroblasts thiab txhawb lawv cov apoptosis.

6. Tiv thaiv kom tsis txhob muaj menyuam thiab muaj cov tshuaj hormones

Luteolin muaj qhov tseem ceeb ntawm kev tiv thaiv kev cog qoob loo. Tom qab kev tswj hwm qhov ncauj, nws tuaj yeem nce qhov hnyav thiab qhov taub ntawm lub tsev menyuam, tuab ntawm endometrium thiab qhov siab ntawm nws cov epithelial hlwb. Thaum cawv tau siv ua ke, nws muaj cov tshuaj tiv thaiv estrogen.

7. Cov nyhuv ntawm cov hlab ntsha

Luteolin tuaj yeem tiv thaiv vascular endothelial txoj kev loj hlob zoo (VEGF) -mus luav corneal angiogenesis hauv vivo; nws tuaj yeem tiv thaiv qog kev loj hlob thiab angiogenesis hauv murine xenograft qog qauv; nws tuaj yeem tiv thaiv VEGF-induced tib neeg txoj hlab ntaws endothelial cells (HUVECs) hauv vitro Ciaj sia taus thiab loj hlob. Nws tuaj yeem tiv thaiv kev nthuav dav thiab DNA sib txuas ntawm cov leeg leeg leeg cov leeg ua rau platelet-tau txais kev loj hlob-BB (PDGF-BB), thiab tuaj yeem thaiv lub voj voog ntawm tes hauv G1 theem. Nws tuaj yeem ua kom nruj-txo qis qhov kev nruj ntawm phenylephrine ua ntej txwv cov hlab ntshav, tiv thaiv cov vasoconstriction tshwm sim los ntawm cov poov tshuaj siab, muaj cov hlab ntshav so, thiab nws cov vasodilation zoo tsis yog endothelial-dependent, thiab nws cov txheej txheem ntawm kev nqis tes yog cuam tshuam ncaj qha rau kev cuam tshuam ncaj qha ntawm qhov hluav taws xob-nyob ntawm cov calcium raws, Tus txais txais-ua haujlwm calcium raws, tso tawm cov tshuaj calcium hauv lub cev, thiab ua kom cov poov tshuaj raws tau cuam tshuam, tab sis tsis muaj dab tsi ua nrog α thiab β receptors.

8. Lwm yam

Luteolin hmoov tuaj yeem tiv thaiv ntau yam kab mob thiab kab mob, xws li Staphylococcus aureus, Escherichia coli, herpes simplex virus, polio virus, Coxsackie B3 virus thiab ntxiv rau. Nws tuaj yeem tiv thaiv kev ua haujlwm ntawm HIV-1 integrase ntawm HIV, thiab muaj peev xwm tiv thaiv kab mob HIV. Luteolin tuaj yeem khi rau s2 protein ntawm qhov mob hnyav ua pa nyuaj (SARS) tus kabmob coronavirus, yog li txwv tsis pub tus kabmob nkag los ntawm tus tswv tsev. Luteolin kuj muaj qhov cuam tshuam tiv thaiv Leishmania donovani, thiab txwv nws txoj kev loj hlob los ntawm kev txwv qhov cuam tshuam ntawm Leishmania donovani topoisomerase I thiab topoisomerase II. Ntxiv rau, luteolin kuj muaj cov tshuaj tiv thaiv kab mob tiv thaiv kab mob.

Daim ntawv thov:

1.luteolin hmoov muaj lub luag haujlwm tiv thaiv kab mob, tiv thaiv kab mob thiab tiv thaiv kab mob; luteolin hawb pob

2.luteolin hmoov muaj cov nyhuv tiv thaiv qog. Tshwj xeeb yog muaj kev tiv thaiv zoo ntawm mob qog noj ntshav prostate thiab mob qog noj ntshav lub mis;

3.luteolin hmoov muaj nuj nqi cuam tshuam thiab tiv thaiv vascular;

4.luteolin hmoov tuaj yeem txo qis qib ntawm kab mob siab fibrosis thiab tiv thaiv lub siab ntawm lub cev los ntawm kev puas tsuaj

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