Polygonum Cuspidatum Extract

Polygonum Cuspidatum Extract yog dab tsi?

Polygonum cuspidatum extractyog tshuaj tua kab mob, antithrombotic, antiinflammatory thiab antianaphylaxis. Nws tuaj yeem pab txhawm rau tiv thaiv mob qog noj ntshav, tshwj xeeb tshaj yog mob cancer mis, antioxidate, ncua kev laus, tiv thaiv pob txha, dementia rau cov neeg laus, qis cholesterolin thiab txo cov kev mob ntshav khov.

Polygonum cuspidatum extract yog cov khoom lag luam tawm hauv paus los yog rhizome ntawm Polygonum cuspidatum. Cov kev lag luam tawm cov khoom lag luam feem ntau yog ua kom muaj cov resveratrol 20%, 50%, 8Chemicalbook 0%, 99%. Nws muaj cov teebmeem ntawm kev tiv thaiv cov hlab plawv, tiv thaiv daim siab thiab txhawb cov leeg hauv plab, thiab tiv thaiv qog ntshav. Polygonum cuspidatum extract tau siv dav hauv ntau qhov kev lag luam xws li tshuaj, khoom siv kho mob, tshuaj pleev ib ce, thiab lwm yam, thiab muaj qhov xav tau loj nyob hauv thoob ntiaj teb ua lag luam.

Khoom siv koob(trans-3,5,4' -trihydroxystilbene), zwm rau cov chav kawm polyphenolic sib txuas ua ke hu ua stilbenes, pom feem ntau ntawm cov tawv nqaij liab txiv hmab thiab hauv paus ntawm Polygonum cuspidatum Sieb. cov tshuaj oriental tau siv los kho cov kab mob ntawm cov hlab ntsha, lub siab thiab kev ua neej. Resveratrol yog ib hom roj-soluble uas tshwm sim hauv trans thiab cis teeb tsa ob qho tib si- thiab trans-resveratrol kuj tshwm sim xws li glucosides. Resveratrol-3-O-beta-glucoside tseem hu ua piceid.

Kev tshawb nrhiav kuj tau qhia txog Polygonum cuspidatum extract tuaj yeem tiv thaiv kev tsim cov khoom lag luam qib siab glycation kawg, lossis HNUB NYOOG. Cov no yog cov collagen-ua kom cov protein thiab cov rog uas tshwm sim hauv daim tawv nqaij vim qhov tshuaj tiv thaiv los ntawm kev cuam tshuam rau cov suab thaj. Tshuav tsis kuaj, HNUB NYOOG tuaj yeem pab ua rau wrinkles thiab ploj ntawm khov.

Cov Lus Qhia Yooj Yim:

Polygonum Cuspidatum Extract Cov Nyiaj Pab:

Tshuaj Tawv Los Sib Xws- Resveratrol yog ib qho phytoalexine tshwm sim hauv cov nroj tsuag tshuaj ntsuab. Cov tshuaj lom neeg no yog tsim los ntawm Japanese Knotweed.

Peb xav hais tias qhov ua haujlwm ntawm antitumor thiab antimetastatic ntawm resveratrol tej zaum vim yog qhov inhibition ntawm DNA synthesis hauv LLC cov hlwb thiab qhov inhibition ntawm LLC-ntxias neovascularization thiab tube tsim (angiogensis) ntawm HUVEC los ntawm resveratrol.

Apoptosis- Lub hom phiaj ntawm txoj kev tshawb no yog txhawm rau soj ntsuam kev loj hlob inhibitory thiab apoptosis ‐ ntxias cov teebmeem thiab cov txheej txheem ntawm Polygonum cuspidatum cov hauv paus hauv kev mob qog nqaij hlav hauv qhov ncauj.

Cov tshuaj methanol extract ntawm P. cuspidatum (MEPC) inhibited qhov loj hlob ntawm qog nqaij hlav cancer hauv qhov ncauj los ntawm kev ua kom cov avpase ap apoptosis tiv. Protein thiab mRNA cov qib qhia kev sib txawv thiab cov transactivation ntawm Cov Khoom Tshwj Xeeb 1 (Sp1) tau txo qis hauv KB hlwb tau kho nrog MEPC.

Cov txiaj ntsig tau los ntawm qhov kev kawm no pom zoo tias MEPC, nws cov seem, thiab Emodin tej zaum yuav yog cov khoom siv bioactive los ua rau apoptosis mechanism dhau los ntawm kev down kev cai ntawm Sp1 hauv cov qog nqaij hlav hauv qhov ncauj.

Kev Cuam Tshuam- Resveratrol tau pom tias muaj kev cuam tshuam los tiv thaiv kev tiv thaiv kab mob thiab tshuaj tua kab mob hauv vitro thiab hauv cov tsiaj ua qauv.Qhov hom phiaj ntawm txoj kev tshawb no yog tshawb xyuas qhov tshwm sim ntawm Polygonum cuspidatum extract (PCE) uas muaj cov resveratrol rau kev tiv thaiv oxidative thiab mob hauv ib qho kev ua si. (10 ib qho) ntawm cov nyhav ib txwm noj qab haus huv tau raug randomized rau cov placebo lossis PCE uas muaj 40 mg resveratrol txhua hnub rau 6 wk. PCE uas muaj cov resveratrol muaj cov kev hloov kho zoo rau kev ntxhov siab oxidative thiab inflammatory. Txoj kev tshawb no tom ntej no tau sim lub peev xwm ntawm ib qho kev xav ntawmpolygonum cuspidatum paus extract(PCE) rau inhibit nas mob pob ntseg ua teb rau cov lus thov ntawm 12-O- tetradecanoylphorbol-13-acetate (TPA).

PCE kev kho mob ntawm txhua txhua koob tau txo qhov ntsej pob ntseg uas piv rau TPA tswj. PCE teb yog koob tshuaj-tiv thaiv thiab 2.5 mg PCE cuam tshuam txhua tus cim ntawm o ua rau muaj kev txwv ntau dua li indomethacin (0.5 mg). MPO cov haujlwm tau raug txwv ntawm PCE koob tshuaj ≥ 1.25 mg / pob ntseg. Trans- resveratrol inhibited mob ntawm cov tshuaj txhaj sib piv.

PCE inhibits kev txhim kho ntawm edema thiab neutrophil infiltration nyob rau hauv TPA-kho nas pob ntseg qauv ntawm cov mob txha caj qaum.

Hepaprotective- Hauv kev kawm tam sim no, kev cuam tshuam hypolipidemic ntawm polydatin, qhov sib txuas los ntawm Polygonum cuspidatum Sieb. et Zucc, ntawm kab mob hyperlipidemic tau soj ntsuam. Peb caug-ob tus luav tau pub lub cev muaj roj / rog siab ntau ntau nyob rau 6 lub lis piam thiab lwm yim tus txiv neej luav tau noj cov zaub mov tseem ceeb raws li kev tswj tau zoo txhua zaus. tus neeg sawv cev hauv chaw kho mob. Polygonum cuspidatum (PC) tau siv rau kev kho mob rau mob caj dab thiab mob tso zis rau hauv cov tshuaj ntsuab.

Hauv qhov kev tshawb nrhiav tam sim no, tshuaj tiv thaiv analgesic thiab anti-inflammatory cuam tshuam ntawm ethyl acetate extract ntawm PC (EAPC) tau tshawb xyuas hauv vivo thawj zaug.Furthermore, EAPC zoo inhibited cov lus teb zoo ntawm c-reactive protein thiab rheumatoid factor piv rau kev tswj tsis tau. Qhov peb tshawb pom tau hais tias EAPC tuaj yeem yog tus muaj peev xwm tshaj lij rau kev kho mob caj dab.

Mob Cancer- Resveratrol, ua los ntawm Suav tshuaj ntsuab tshuaj polygonum cuspidatum cag tawm, yog paub tias yuav tiv thaiv kom txhob muaj ntxeem tau thiab muaj metastasis ntawm tib neeg mob qog nqaij hlav cancer (CRC), nyob rau hauv ntev uas tsis muaj coding Metastasis Associated Lung Adenocarcinoma Transcript 1 (RNA-MALAT1) tseem ua lub luag haujlwm tseem ceeb. Cov.

Peb pom tias qhov cuam tshuam los tiv thaiv cov qog ntawm resveratrol ntawm CRC yog los ntawm kev tiv thaiv Wnt / β-catenin cov paib, yog li cov lus qhia ntawm nws cov hom phiaj xws li c-Myc, MMP-7, nrog rau kev qhia ntawm MALAT1.

Qhov kev tshawb pom ntawm peb li no tau muab cov pov thawj ua tseem ceeb ua ntej txhawb nqa kev siv resveratrol yav tom ntej hauv kev tiv thaiv thiab kho CRC.

Hauv qhov kev tshawb nrhiav tom ntej no, lawv tau mus soj ntsuam cov sib txawv sib txawv uas yuav muaj txiaj ntsig zoo rau kev siv tshuaj kho mob.One muaj pes tsawg leeg cais los ntawm cov hauv paus hniav ntawm Polygonum cuspidatum los ntawm cytotoxicity raws fractionation thiab nrhiav tau los ntawm HPLC-MS, UV scanning thiab IR.

Qhov no muaj pes tsawg leeg tau txheeb xyuas tias yog trans-thiab cis-resveratrol. Nws tuaj yeem tshwj rau kev cuam tshuam loj hlob ntawm ntau cov qog nqaij hlav cancer tab sis tsis yog tib neeg lub siab lub ntsej muag. Peb tshawb nrhiav cytotoxicity ntawm resveratrol rau adriamycin-resistant MCF-7 cell hauv virtro. Resveratrol yog ib qho tshuaj tiv thaiv kab mob tshiab uas tsis muaj tshuaj lom ntau dua thiab ua kom tau zoo dua nyob hauv Polygonum cuspidatum.

Angiogenesis- Qhov aqueous extract ntawm 24 tshuaj ntsuab ib txwm siv los kho ischemic mob plawv hauv chaw kho mob hauv Suav teb tau raug kuaj rau lawv cov haujlwm hauv vitro angiogenic, lwm nees nkaum plaub kab ke siv los tiv thaiv mob qog lossis tshuaj tiv thaiv mob hauv Suav teb tau raug kuaj rau lawv cov nyob hauv vitro. anti-angiogenic kev ua. Polygonum cuspidatum thiab Scrophularia ningpoensis elicited tseem ceeb inhibition ntawm ib qho kev haum ntawm 1g qhuav tshuaj ntsuab / ml.

Nco Ntsoov- Polydatin yog ib qho ntawm feem ntau ntsib stilbenes ntawm cov xwm thiab ib qho tseem ceeb ntawm Suav tshuaj ntsuab Polygonum cuspidatum. Qhov kev tshawb nrhiav no yog tshawb xyuas qhov cuam tshuam ntawm polydatin ntawm kev kawm thiab nco kev ua rau muaj kev puas siab puas ntsws los ntawm kev mob hlwb hauv cov nas, nrog rau lub peev xwm.

Cov txiaj ntsig no tau qhia tias polydatin tso tawm kev kho mob lub peev xwm rau vascular dementia, uas feem ntau yuav cuam tshuam, tsawg kawg ntawm ib feem, rau nws cov kev ua los tiv thaiv oxidant thiab kev tiv thaiv ncaj qha ntawm neurons.

Daim ntawv thov:

1. Tiv thaiv lub plawv thiab cov ntshav ncig, txo qis roj cholesterol, thiab tiv thaiv cov ntshav txhaws uas tuaj yeem ua rau lub plawv nres thiab mob hlab ntsha tawg.
2. Tiv thaiv cell' s DNA. Nws yog cov tshuaj antioxidant haib. Antioxidants tuaj yeem pab tiv thaiv cell puas tsuaj los ntawm dawb radicals. Dawb radicals tsis ruaj khov atoms los ntawm kev ua qias tuaj, lub hnub ci thiab peb lub cev ntuj hlawv cov roj uas tuaj yeem ua rau mob qog noj ntshav, laus thiab lub hlwb tsis zoo.
3. Txo cov cholesterolin thiab cov ntshav viscosity, txo kev pheej hmoo ntawm cov hlab ntsha, cov kab mob cardio-cerebrovascular thiab kab mob plawv.
4. Los tiv thaiv tus kab mob thiab pab tiv thaiv kev tiv thaiv, tiv thaiv Staphylococcus aureus, Micrococcus catarrhalis, Bacillus coli, aeruginosus Bacillus, muaj cov tshuaj tiv thaiv zoo dua nrog Orphan virus, ua npaws blisters tus kab mob, tus kab mob enteric thiab Kesaqi virus.

Qhov zoo tshaj plaws Polygonum Cuspidatum Extract tsum

Undersun nyiam kev sib raug zoo ntev nrog peb cov neeg vim tias peb tsom rau cov neeg siv khoom thiab muab cov khoom lag luam zoo. Yog tias koj txaus siab rau peb cov khoom lag luam, peb yoog tau nrog kho kom haum cov kev txiav txim siab kom haum koj cov kev xav tau tshwj xeeb thiab peb lub sijhawm coj ceev ntawm kev txiav txim tuaj yeem lav koj yuav tau saj zoo ntawm peb cov khoom raws sij hawm. Peb kuj tseem tsom rau kev pabcuam ntxiv tus nqi. Peb muaj nyob rau cov lus nug kev pabcuam thiab cov ntaub ntawv los txhawb koj txoj kev lag luam.

Vim li cas Xaiv Undersun Polygonum Cuspidatum Extract?

Undersun tshwj xeeb hauv polygonum cuspidatum paus extract rau ob peb xyoo, peb muab cov khoom lag luam nrog tus nqi sib tw, thiab peb cov khoom yog qhov zoo tshaj plaws thiab yauv mus ua cov kev kuaj xyuas nruj, kom ntseeg tau tias nws muaj kev nyab xeeb rau noj thoob ntiaj teb.

Qhov twg yuav Polygonum Cuspidatum Extract?

Cia li xa email musherbext@undersun.com.cn, lossis xa koj qhov yuav tsum tau ua hauv daim foos hauv qab, peb yog cov haujlwm pabcuam lub sijhawm twg los tau!