Raws li cov neeg nyiam cov khoom xyaw ntxiv los ntawm cov nroj tsuag ntuj rau kev tswj ntshav qab zib, mulberry nplooj extract tau dhau los ua kev xaiv nrov hauv cov ntshav qab zib cov qauv vim nws cov khoom tshwj xeeb bioactive, tshwj xeeb tshaj yog1-Deoxynojirimycin (DNJ).
Peb tab tom pom kev xav tau ntau zuj zus los ntawm cov khoom noj khoom haus ntxiv, cov chaw tsim khoom noj khoom haus, thiab cov neeg tsim khoom noj haus, txhua tus nrhiav kev daws teeb meem ntshav qab zib. Kab lus no yuav piav qhia vim li cas mulberry nplooj extract tau dhau los ua cov khoom muaj txiaj ntsig hauv cov qauv ntshav qab zib niaj hnub no.
Mulberry nplooj Extract yog dab tsi?
Mulberry nplooj extractyog muab los ntawm nplooj ntawm Morus alba tsob ntoo, ib txwm siv nyob rau hauv Esxias herbal tshuaj rau metabolic thiab circulatory noj qab haus huv. Cov extract yog tsim los ntawm kev ziab thiab ua cov nplooj mulberry -feem ntau yog siv cov txheej txheem xws li dej kub rho tawm, concentration, pom, thiab tshuaj tsuag kom qhuav- kom tau cov hmoov uas haum rau kev noj zaub mov, khoom noj khoom haus, dej haus, lossis tshuaj yej.
Mulberry nplooj extract feem ntau yog xim av - daj hmoov. Nws khaws ntau yam bioactive Cheebtsam, suav nrog flavonoids, alkaloids, polysaccharides, amino acids, thiab ntau yam vitamins thiab kab kawm . 1-Deoxynojirimycin (DNJ) yog piperidine polyhydroxy alkaloid cais los ntawm mulberry nplooj. DNJ yog tshwj xeeb rau mulberry nplooj hauv cov nroj tsuag.
Lub luag haujlwm tseem ceeb: DNJ
DNJ yog ib qho iminosugar alkaloid tshwj xeeb uas muaj nyob rau hauv mulberry nplooj. Nws lub luag haujlwm tseem ceeb ntawm kev ua haujlwm yog inhibition ntawm plab hnyuv carbohydrate-digesting enzymes - tshwj xeeb tshaj yog -glucosidase. Los ntawm kev thaiv cov enzyme no, DNJ txo qhov kev ua txhaum ntawm cov carbohydrates nyuaj (xws li cov hmoov txhuv nplej siab thiab sucrose) rau hauv cov suab thaj yooj yim, yog li ua kom cov piam thaj nqus mus rau hauv cov hlab ntsha.
Standardizing mulberry nplooj extract mus rau ib tug tshwj xeeb DNJ concentration pab kom zoo ib yam physiological teebmeem. Piv txwv li, kev tshawb fawb soj ntsuam tau siv cov khoom xa tawm me me li ~ 6-9 mg DNJ ib qho kev pabcuam kom ua tiav cov txiaj ntsig glycemic ntsuas.
DNJ specification feem ntau yog los ntawm:
0.5% DNJ (extract rau kev noj qab haus huv)
1% DNJ (extract rau cov ntshav qab zib cov mis)
3-5% DNJ (siab- cov qauv tsim muaj zog)
Undersuntshwj xeeb hauv kev tsim khoom0.5%, 1%, 2%, 5%, thiab 10% DNJlos ntawm cov txheej txheem xws lidej ntshiab extraction, membrane filtration, thiab decolorization. Peb DNJ tsis muaj cov kuab tshuaj residue, solubility zoo dua, thiab tsis muaj cov khoom ntxiv.Nws yog qhov kev xaiv zoo tshaj plaws rau cov khoom lag luam nrhiav daim ntawv lo huv.
Mulberry nplooj Extract txhawb ntshav qab zib li cas?
Los ntawm inhibiting carbohydrate- digesting enzymes, mulberry nplooj extract - ntawm DNJ - dampens post- noj qab haus huv spikes (postprandial glycemia). Qhov no ua rau nws muaj txiaj ntsig zoo rau cov ntshav qab zib cov qauv tsim los txhawb kev sib npaug ntawm glycemic, tshwj xeeb tshaj yog nyob rau hauv cov khoom lag luam tsom rau cov tib neeg uas muaj cov piam thaj tsis txaus siab lossis cov neeg nrhiav kev noj qab haus huv. Ib qho kev sim randomized pom tias mulberry nplooj extract txo qis tom qab- pluas mov qabzib los ntawm 24-29% hauv cov neeg laus noj qab haus huv noj carbohydrate- zaub mov nplua nuj.
Tsis tas li ntawd, cov pov thawj pom tau hais tias mulberry nplooj extract tuaj yeem txhim kho insulin rhiab heev los ntawm kev taw qhia txoj hauv kev khi rau cov piam thaj. Hauv cov qauv tsiaj, mulberry nplooj extract (thiab DNJ) tau pom tias yuav qhib IRS-1 / PI3K / Akt txoj hauv kev hauv cov leeg pob txha, txhim kho kev hloov pauv ntawm cov piam thaj hauv cov ntshav (GLUT4) mus rau cov cell membrane thiab txhawb nqa cov piam thaj tshem tawm los ntawm cov ntshav.
Synergy nrog lwm cov ntshav qab zib cov khoom xyaw
Hauv ntau cov qauv ntshav qab zib, mulberry nplooj extract tsis yog siv ib leeg. Nws cov txheej txheem - qeeb qeeb kev nqus ntawm carbohydrates - tuaj yeem ua ke nrog lwm cov khoom xyaw uas tswj cov piam thaj los tsim cov khoom lag luam metabolic txhawb nqa ntau dua. Piv txwv li:
- Nrog cov khoom sib xyaw uas txhim kho cov tshuaj insulin (xws li,chromium,ua berberine, alpha{0}}lipoic acid), mulberry nplooj extract qhov nqus-slowing nyhuv tuaj yeem txo glycemic load thaum lwm cov khoom xyaw txhim kho peripheral qabzib.
- Nrogfiber ntau cov khoom xyawlos yogsoluble noj fibers, mulberry nplooj extract tuaj yeem pab ntxiv qhov nruab nrab carbohydrate digestion thiab qeeb cov piam thaj tso tawm.
- Nrog botanical antioxidants (xws li,flavonoids, polyphenols), cov qauv tsim yuav tau txais txiaj ntsig ntxiv - xws li txo qis oxidative kev nyuaj siab, txhim kho cov cim qhia ntawm insulin, thiab txhawb kev noj qab haus huv metabolic tshaj li kev tswj hwm qabzib.
Vim hais tias mulberry nplooj extract yog cov nroj tsuag -raws li thiab kuj nruab nrab nyob rau hauv saj, nws integrates zoo rau hauv multi- cov khoom xyaw. Qhov kev hloov pauv no ua rau nws zoo tagnrho rau cov ntawv xa khoom sib txawv - los ntawm cov tshuaj ntsiav mus rau cov khoom noj thiab dej haus.
Cov pov thawj kho mob txhawb nqa Mulberry Leaf's Glucose Benefits
Nov yog ob qho piv txwv ntawm cov ntaub ntawv-tsav:
1. Hauv kev tshawb fawb randomized, ob-dig muag, kev tswj cov placebo, cov neeg koom nrog uas tau noj cov nplooj mulberry nrog rau kev sib tw sucrose tau ntsib cov ntshav qabzib tsawg dua tom qab noj mov thiab cov tshuaj insulin ntau dua piv nrog cov placebo. Txoj kev tshawb no tau tshaj tawm cov lus teb ntawm cov piam thaj ntau dua, tsis txhob muaj cov tshuaj hypoglycemia uas tshwm sim hauv pawg placebo.
2. Hauv lwm qhov kev sim sib tw nrog cov neeg uas muaj cov piam thaj hauv cov metabolism tsis zoo, kev noj cov nplooj mulberry extract enriched hauv DNJ (3, 6, lossis 9 mg) ua rau txo qis glycemic teb tom qab 200 g boiled nplej dawb; Tshaj li 12 lub lis piam ntxiv (6 mg DNJ, tid), cov neeg koom tau pom tias muaj kev txhim kho postprandial glycemic tswj raws li qhia los ntawm qib siab dua 1,5-anhydroglucitol. Tsis tas li ntawd, ib tus kheej- tswj kev sib tw txoj kev tshawb fawb pom tau hais tias kev noj cov nplooj mulberry extract nrog rau ntau yam carbohydrates (sucrose, maltose, maltodextrin) txo qis glycemic Performance index (GI) ntawm cov carbs - piv txwv li, txo cov GI ntawm sucrose los ntawm kwv yees li 33.5% ~ 5% thiab maltose.
Siv nyob rau hauv dej haus, hmoov, thiab Gummies
Raws li cov hmoov nplej extract, mulberry nplooj extract tau yooj yim muab tso rau hauv ntau yam khoom xa tuaj.
- Dej Haus & Tshuaj yej:Mulberry nplooj extract tuaj yeem muab sib xyaw rau hauv npaj- rau- haus dej los yog hmoov.
- Powdered Supplements:Rau cov qauv tshuaj ntxiv, mulberry nplooj extract hmoov - tus qauv rau DNJ - tau yooj yim muab ntim los yog ntsuas rau kev suav nrog hauv cov khoom ntxiv.
- Gummy & Chewables:Vim tias mulberry nplooj extract yog cov nroj tsuag -raws li thiab feem ntau tolerable (tsis muaj zog iab), nws tuaj yeem tsim rau hauv chewables. Ua ke nrog flavors thiab sweeteners, mulberry nplooj extract-raws li gummies.
Tam sim no raws li txoj cai nyob rau hauv txawv teb chaws
- Tebchaws Meskas:Mulberry nplooj extract tau tso cai nyob rau hauv kev noj haus tshuaj raws li DSHEA 1994.
- European Union:Mulberry nplooj extract yog cais raws li Novel Food tshwj tsis yog muaj pov thawj tias yuav siv ua ntej xyoo 1997. Cov tuam txhab yuav tsum nrhiav kev pom zoo ua ntej - ua lag luam. Cov ntawv thov kev noj qab haus huv xav tau EFSA cov ntsiab lus.
- United Kingdom:Tso cai nyob rau hauv cov tshuaj thiab cov khoom noj ua haujlwm. Txhua qhov kev thov ntshav qab zib yuav tsum tau txais kev txhawb nqa los ntawm cov pov thawj tshawb fawb thiab pom zoo los ntawm UKNHCC.
- Nyiv (FOSHU & FFC):Nyiv muaj cov txheej txheem txheej txheem rau cov zaub mov noj qab haus huv. Mulberry nplooj extract feem ntau yog siv hauv FFC-labeled thiab FOSHU- cov khoom pom zoo. Cov ntaub ntawv hais txog cov ntshav qabzib postprandial xav tau cov ntaub ntawv kho mob.
- Lwm cov lag luam Asian:ASEAN thiab South Kauslim txawv ntawm lub tebchaws. Feem ntau tso cai rau mulberry nplooj extract hauv cov tshuaj tab sis txwv tsis pub muaj kab mob.
Xaiv ib lub tuam txhab txhim khu kev qha Mulberry nplooj Extract chaw tsim tshuaj paus
Xaiv lub chaw tsim tshuaj paus txhim khu kev qha mulberry nplooj extract yog qhov tseem ceeb los xyuas kom meej qhov ruaj khov thiab kev nyab xeeb ntawm koj cov qauv thiab qhov cuam tshuam ntawm koj lub hom.UndersunmuajISO, HACCP, Kosher,thiabHalalcov ntawv pov thawj, ua kom muaj kev tswj xyuas nruj. Peb lub tuam txhab muaj ntau yam DNJ specifications, customizable formulations, thiab ua tiav cov ntaub ntawv nrog rauCOA, hnyav- kuaj hlau, thiab cov ntawv ceeb toom microbial. Nrog nws tus kheej lub Hoobkas, pob tshab khoom, thiab muaj peev xwm R & D muaj zog, Undersun muab kev txhawb nqa rau cov tshuaj, khoom noj khoom haus, thiab hom dej haus.Tiv tauj pebhnub no!
FAQ
1. Cov nplooj mulberry tuaj yeem siv rau hauv dej haus?
Yog lawm. Dej- cov qib soluble yog cov cua sov- ruaj khov thiab feem ntau siv hauv RTD cov dej qab zib ua haujlwm.
2. Puas yog mulberry nplooj extract muaj kev nyab xeeb rau lub sijhawm ntev - siv?
Tib neeg cov kev tshawb fawb qhia tau hais tias muaj kev nyab xeeb siab nrog tsawg kawg ntawm kev mob plab hnyuv.
4. Dab tsi yog qhov pom zoo noj txhua hnub?
Cov tshuaj ntau npaum li cas ntawm 500-1500 mg nyob ntawm DNJ concentration thiab hom qauv.
5. Cov mulberry extract puas tuaj yeem ua ke nrog berberine lossis chromium?
Yog lawm. Cov kev sib xyaw ua ke no muaj ntau thiab ua kom pom muaj zog sib koom ua ke hauv cov qauv kev txhawb nqa metabolic.
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Kev siv
https://pubmed.ncbi.nlm.nih.gov/24843505/
https://link.springer.com/article/10.1186/s12986-021-00571-2
