NMN muab cov kev mob tshwm sim
Sab sij huam& Kev Nyab Xeeb
Thaum noj ntawm qhov ncauj: Nicotinamide riboside yog POSSIBLY SAFE thaum siv sijhawm luv. Kev phiv los ntawm nicotinamide riboside feem ntau yog mob me. Cov kev mob tshwm sim yuav suav nrog teeb meem hauv plab xws li xeev siab thiab tsam plab los yog tawv nqaij muaj teeb meem xws li khaus thiab tawm hws ntau dhau.
Tam sim no, tsis muaj kev phiv tshuaj los ntawmnicotinamide mononucleotidetau raug teev tseg nyob hauv tib neeg. Cov kws tshawb nrhiav tau ua rau feem ntau ntawm kev tshawb fawb txog NMN hauv cov nas, uas tau qhia txog cov txiaj ntsig zoo ntawm cov metabolism, lub hlwb ua haujlwm, daim siab, tawv nqaij, cov leeg, pob txha tsim, kev mob plawv, kev tsim tawm, kev tiv thaiv, thiab kev siv lub neej. Kev tshawb xyuas nas ntev ntev kuj pom tias tsis muaj tshuaj lom, muaj kev phiv loj heev, lossis ua rau muaj kev ua neeg tuag thoob plaws 12 lub hlis ncua sijhawm.
Ib tug kawm ntawmNMNnyob rau hauv tib neeg qhia tsis muaj kev txhawj xeeb muaj kev nyab xeeb tom qab noj ib zaug ntawm 100, 250, thiab 500 mg ntawm NMN. Tsib teev tom qab kev tswj hwm qhov ncauj ib leeg ntawm NMN, cov kws tshawb fawb pom tsis muaj kev hloov pauv hauv lub plawv, ntshav siab, ntshav oxygen, lossis lub cev kub. Kev kuaj ntshav tau pom tias tsis muaj qhov hloov pauv ntau, tsuas yog muaj qib plaub lub suab nyob hauv cov ntshav, uas poob rau hauv thaj tsam ib txwm muaj. Txoj kev tshawb no tseem ntsuas kev pw tsaug zog zoo, thiab pom tias tsis muaj qhov sib txawv ua ntej thiab tom qab NMN noj.
Cov kws tshawb fawb xav tau kev tshawb fawb ntxiv ntawm NMN kev tswj hwm hauv tib neeg los txiav txim siab seb puas muaj kev phiv los ntawm kev siv nws. Cov kws tshawb fawb yuav saib cov koob tshuaj uas siab dua 500 mg txhawm rau nrhiav seb lawv puas muaj kev phiv. Kev tshawb nrhiav tseem tuaj yeem txheeb xyuas seb puas yuav noj NMN ncua ntev ua rau muaj kev phiv tshuaj.
Kev Ceev Faj Tshwj Xeeb& Cov lus ceeb toom:
Cev xeeb tub thiab pub niam mis: Tsis muaj' Nyob rau sab muaj kev nyab xeeb thiab zam kev siv.
Rooj ntawv 2
Zoo thiabtsis zoontawm NAM qhia nyob rau hauv tib neeg kev tshawb fawb 1.
| Cuam tshuam Organs thiab Kev Mob 2 | Pom Qhov Teeb Meem | Koob tshuaj thiab sijhawm | Ua tim khawv |
|---|---|---|---|
| Kev muaj txiaj ntsig zoo | |||
| Cov pob qij txha | Txo txo cov khaus hauv cov neeg mob uremic | 550 mg ib hnub ob zaug (4 lub lis piam) | [38] |
| pancreatic β-cell | β-cell muaj nuj nqi khaws cia thiab txhim kho | 25 mg / kg noj txhua hnub (4 lub lis piam) | [18,39] |
| Txo cov feem pua ntawm cov ntshav qab zib muaj mob | 500 mg ib hnub ob zaug (2.5 xyoo) | [19] | |
| Tsis muaj dab tsi cuam tshuam rau qhov tshwm sim ntawm cov mob ntshav qab zib-dawb | 1200 mg rau hnub noj (5 xyoos) | [20] | |
| Kev ua tsis tau zoo hauv kev tiv thaiv lossis ncua sijhawm saib xyuas ntshav qab zib | 1.2 g txhua hnub kom tsawg (3 xyoos) | [21] | |
| Daim tawv nqaij | Yuav txo tau pob txuv txhab thiab mob hnyav | 4% gel thov ob zaug ib hnub (8 lub lis piam) | [26] |
| Attenuated immunosuppression nrog kev hloov pauv hauv cov metabolism thiab apoptosis | 5% tshuaj pleev rau ua ntej kis UV | [40] | |
| Kev siab ntsws | Txhim kho tiv thaiv kev nyuaj siab | 0.5-1.5 g txhua hnub txais tos (3 lub lis piam) | [22] |
| Kev pab cuam los ntawm kev ntxhov siab | Ib koob tshuaj 2 ug 3 h ua ntej coj mus kuaj | [23] | |
| Raum | Qhov qis qis ntshiab ntau ntawm phosphorus, parathyroid hormone, thiab LDL, thiab nce ntshav dej HDL | 500 mg / hnub (nrog thiab nce ntxiv txhua 2 asthiv) (12 lub lis piam) | [41] |
| Daim tawv nqaij tuaj yeem tsis mob melanoma | Txo cov xwm txheej ntawm ntau hom tawv nqaij tawv nqaij thiab actinic keratoses | 500 mg ob zaug ib hnub (4 hli) | [42] |
| Cov Teeb Meem Tsis Zoo | |||
| Cov teebmeem me me | Mob tob hau npus mob taub hau, xeev siab, mob taub hau, kiv taub hau | 1–18 g sai li sai tau | [43,44] |
| Pancreatic β-cell / ntshav | Txo cov tshuaj insulin tsawg dua, muaj kev nyuaj siab ntau dua oxidative (H2O2) | 2 g txhua hnub (2 lub lis piam) | [45,46] |
| Lub siab | Parenchymal-cell raug mob, portal fibrosis thiab cholestasis, raug mob siab | 3, 9 g txhua hnub (10 hnub) | [47] |
| Lymphocytes, platelets | Cov mob toxicity cuam tshuam rau mob qog nqaij hlav thiab mob thrombocytopenia | 1300, 1500 mg txhua hnub (24 lub lis piam) | [48] |
| Raum / platelets | Txo cov ntshav phosphorus thiab thrombocytopenia | 0.52-2 g txhua hnub (3–6 hlis) | [49,50] |
Cov chiv keeb: https: //www.nmn.com/precursors/nmn-benefits-side-effects-dosage
https://www.webmd.com/vitamins/ai/ingredientmono-1560/nicotinamide-riboside
