Dab tsi yog artemisinin siv rau
Tau muaj qhov nce ntxiv yog rov tshuaj xyuas cov tshuaj ib txwm muaj nyob thoob ntiaj teb, nrog kev tshawb fawb dav txog ntau hom tsiaj thiab lawv cov khoom kho mob tau ua tiav. Kev siv tshuaj ntsuab cog ib txwm tau hais los ua lwm yam tshuaj uas tsis tshua muaj feem ua rau muaj kev phom sij, tsis zoo li cov tshuaj tsim los ntawm cov tshuaj tsim tawm [1].Artemisia txhua xyooL. (Asteraceae) yog tshuaj ntsuab txhua xyoo nyob rau Asia, thiab tau siv rau ntau pua xyoo hauv cov tshuaj Asian rau kev kho thiab tiv thaiv kev kub taub hau thiab ua daus no. Ntau yam sib xyaw tau muab rho tawm los ntawm Artemisia annua L. xws li sesquiterpenoids, flavonoids, coumarins, lipids, phenolics, purines, steroids, triterpenoids, aliphatics, thiab artemisinin.
Lub hauv paus tseem ceeb hauv Artemisia annua L., artemisinin, muaj tus qauv C15H22O15 thiab muaj tus choj peroxide (COOC) (Daim duab 1). Artemisinin tau siv dav rau kev kho mob malaria rau ob xyoo dhau los [4]. Ib qho ntxiv, artemisinin paub tias muaj cov tshuaj tua kab mob, tiv thaiv kab mob, tiv thaiv kab mob, tiv thaiv kab mob, tiv thaiv kab mob, thiab tiv thaiv kev ua haujlwm.
Artemisinin Dosage
Kev siv tshuaj ntau npaum li cas rau kev hais lus tswj hwm Artemisinin yog 500-1000 mg (10-20 mg/kg) nyob rau thawj hnub, tom qab ntawd 500 mg txhua hnub rau 4 hnub.
Artemisinin suppositories tau muab rau cov neeg mob malciparum mob hnyav, ntawm koob tshuaj 600-1200 mg thaum pib, tom qab ntawd 400-600 mg 4 h tom qab thiab 400-800 mg txhua hnub rau 3 hnub.
Feem ntau, mefloquine 15-25 mg/kg tau muab 24-72 h tom qab pib kho Artemisinin.
Artemisinin yog siv los kho
Artemisinin yog cov tshuaj tau los ntawm cov neeg Esxias cog Artemisia annua. Cov paj ntoo uas muaj ntxhiab no muaj nplooj zoo li nplooj thiab paj daj. Tau ntau dua 2,000 xyoo, nws tau siv los kho tus mob ua npaws. Nws' kuj yog kev kho mob zoo rau mob npaws.
Artemisinin yog siv los kho tus mob npaws zoo thiab tau kawm txog kev kho mob qog noj ntshav. Cov kev tshawb fawb thaum ntxov qhia tau tias muaj txiaj ntsig zoo, tab sis kev tshawb fawb muaj tsawg. Tsis tas li, tsis muaj kev sim tshuaj loj tau ua tiav.
Yog tias koj muaj mob qog noj ntshav, koj yuav tsum tseem nrhiav kev kho mob qog noj ntshav ib txwm muaj. Tham nrog koj tus kws kho mob txog kev sim tshuaj, xws li artemisinin, kom tau txais cov ntaub ntawv ntau ntxiv tshwj xeeb rau koj rooj plaub.
Artemisinin covid-19
Kev kis mob hnyav nrog mob hnyav ua pa nyuaj rau tus mob coronavirus 2 (SARS-CoV-2) 1,2 muaj txog rau Lub Rau Hli 2021 thoob ntiaj teb tau cuam tshuam nrog ntau dua 3.9 lab tus neeg tuag los ntawm tus mob coronavirus 2019 (COVID-19) 3,4,5. Tus kab mob ua npaws ua npaws thiab kab mob muaj feem kis tau zoo thiab feem ntau ua rau muaj kev phom sij rau lub neej. Remdesivir tsuas yog Kev Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) tau pom zoo ncaj qha ua tshuaj tua kab mob rau kev kho mob ntawm COVID-19; txawm li cas los xij, nws cov txiaj ntsig kev kho mob tsis ntev los no tau tawm tsam 6,7,8. Yog li, kev kho COVID-19 tseem muaj kev txhawb nqa ntau nrog qhov xav tau ceev los txheeb xyuas cov tshuaj tiv thaiv kab mob ntxiv rau SARS-CoV-2. Ib txoj hauv kev ntxim nyiam yog rov ua dua cov tshuaj twb tau tso cai rau lwm yam kab mob. A. annua cov nroj tsuag tau ua haujlwm los kho tus mob malaria hauv Tshuaj Suav, nrog rau kev sim tib neeg, thiab tau siv dav hauv ntau lub tebchaws African, txawm tias tawm tsam WHO cov lus pom zoo.
Artemisinin vs artesunate
Artesunate sawv cev rau ib nrab ntawm cov khoom sib xyaw ntawm artemisinin uas tau txhim kho cov dej sib tov. Cultivar ntawm Suav tshuaj ntsuab Artemisia annua L. (qinhao lossis qab zib wormwood) thiab nws txoj haujlwm nquag artemisinin (qinhaosu).
Puas yog artemisinin muaj cov kev mob tshwm sim
Txawm hais tias artemisinin yog ib qho tshwm sim ib txwm muaj, noj nws cuam tshuam nrog kev pheej hmoo. Hauv cov koob tshuaj pom zoo, nws yuav muaj kev nyab xeeb rau tus neeg noj tshuaj artemisinin los kho tus mob npaws npaws lossis kub cev.
Txawm li cas los xij, tib neeg yuav ntsib cov kev mob tshwm sim hauv qab no:
tawv nqaij ua pob, tom qab siv tshuaj pleev
kiv taub hau
nrov hauv pob ntseg
tsis hnov lus
ntuav
xeev siab
tshee
teeb meem daim siab
Puas yog artemisinin yog tshuaj tua kab mob
Artemisinin, yog ib qho ntawm cov tshuaj sib txuas ua tshuaj lom neeg, nrog rau kev ua haujlwm tiv thaiv kab mob npaws tau ua tiav cais los ntawm A. annua. Lwm yam tshaj li kev ua haujlwm antimalarial, artemisinin tau pom tias yog cov tshuaj tua kab mob zoo, tshuaj tua kab mob, tshuaj tua kab mob, thiab tshuaj tua kab mob. Cov khoom tiv thaiv kab mob ntawm artemisinin tau raug kuaj ntawm ntau yam kab mob, xws li Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, thiab Mycobacterium intracellulare. Kev nthuav dav dav ntawm lwm cov tshuaj metabolites thib ob tau pom thiab sib sau ua ke ntawm huab cua ntawm A. annua.
Txog rau ntau artemisinin, thov hu rau peb ntawm email:herbext@undersun.com.cn
Cov ntaub ntawv: https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC4297758/
http://www.antimicrobe.org/drugpopup/artemisinin.htm
https://www.healthline.com/health/artemisinin-cancer#outlook
https://www.nature.com/articles/s41598-021-93361-yog
https://academic.oup.com/cid/article/47/6/804/325924
https://www.medicalnewstoday.com/articles/324577#side-effects-and-risks
https://www.hindawi.com/journals/bmri/2014/215872/
