Cov txiaj ntsig Artemisinin
Lub hauv paus tseem ceeb hauv Artemisia annua L., artemisinin, muaj tus qauv C15H22O15 thiab muaj tus choj peroxide (COOC) (Daim duab 1).Artemisinintau siv dav rau kev kho mob malaria rau ob xyoo dhau los [4]. Ib qho ntxiv, artemisinin paub tias muaj cov tshuaj tua kab mob, tiv thaiv kab mob, tiv thaiv kab mob, tiv thaiv kab mob, tiv thaiv kab mob, thiab tiv thaiv kev ua haujlwm.
Cov tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob, thiab tshuaj tiv thaiv kab mob ntawm artemisinin muab los ntawm dej, methanol, ethanol, lossis acetone rho tawm ntawm Artemisia annua L. tau tshuaj xyuas. Tag nrho 4 cov tshuaj artemisinin muaj cov tshuaj tiv thaiv kab mob. Ntawm cov no, cov tshuaj acetone muaj qhov cuam tshuam loj tshaj ntawm lipopolysaccharide-induced nitric oxide (NO), prostaglandin E2 (PGE2), thiab proinflammatory cytokine (IL-1β, IL-6, thiab IL-10). Kev tshuaj xyuas cov tshuaj tiv thaiv kab mob antioxidant tau tshaj tawm tias ethanol extract muaj qhov siab tshaj plaws dawb radical scavenging kev ua si, (91.0 ± 3.2%), zoo ib yam li α-tocopherol (99.9%). Cov tshuaj rho tawm muaj cov tshuaj tua kab mob tiv thaiv kab mob periodontopathic Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum subsp. Animalis, Fusobacterium nucleatum subsp. polymorphum, thiab Prevotella intermedia. Txoj kev tshawb no qhia pom tias Artemisia annua L. cov tshuaj muaj cov tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob, thiab tshuaj tua kab mob thiab yuav tsum raug txiav txim siab siv rau hauv cov khoom lag luam kws kho mob kho kab mob hniav.
Kuv puas tuaj yeem noj artemisinin txhua hnub?
Kev siv tshuaj ntau npaum li cas rau kev tswj hwm qhov ncauj Artemisinin yog 500-1000 mg (10-20 mg/kg) nyob rau thawj hnub, tom qab ntawd 500 mg txhua hnub rau 4 hnub. 600-1200 mg pib, ua raws li 400-600 mg 4 h tom qab thiab 400-800 mg txhua hnub rau 3 hnub.Generally, mefloquine 15-25 mg/kg tau muab 24-72 h tom qab pib kho Artemisinin.
Puas yog artemisinin muaj kev phiv?
Artemisinintuaj yeem noj tau ntawm qhov ncauj, txhaj rau hauv koj cov leeg, lossis tso rau hauv qhov quav raws li qhov quav. Qhov kev rho tawm no cuam tshuam nrog ob peb yam kev phiv, tab sis nws yuav tsum tsis suav nrog lwm yam tshuaj tshwj tsis yog koj tus kws kho mob pom zoo.
Qee qhov tshwm sim tshwm sim ntawm artemisinin yog:
daim tawv nqaij ua pob
xeev siab
ntuav
tshee
teeb meem daim siab
Koj yuav tsum tsis txhob noj cov tshuaj artemisinin yog tias koj noj tshuaj tiv thaiv qaug dab peg. Nws tuaj yeem ua rau qaug dab peg lossis ua rau cov tshuaj tsis muaj zog. Cov neeg uas muaj teeb meem plab zom mov yuav tsum tsis txhob noj artemisinin.
Koj yuav tsum noj tshuaj artemisinin ntev npaum li cas?
Cov artemisinins (ar tem' nyob rau hauv), suav nrog artesumate, arteeter, artemether, artemisinin, thiab dihydroartemisinin, yog cov khoom siv los ntawm Suav tshuaj ntsuab hu ua&"qing hao &"; los yog tsob ntoo wormwood qab zib (Artemisia annua). Cov artemisinins muaj cov tshuaj tiv thaiv kab mob hauv vitro thiab hauv vivo thiab ntseeg tias ua los ntawm kev tso tawm cov dawb radicals rau hauv cov kab mob vacuoles. Artemisinin derivatives tam sim no yog cov tshuaj tiv thaiv kab mob siab tshaj plaws muaj thiab tau tshaj tawm thoob ntiaj teb los ua ib feem tseem ceeb ntawm kev kho mob npaws npaws, ib txwm ua ke nrog lwm cov tshuaj tiv thaiv kab mob los tiv thaiv kev tiv thaiv xws li amodiaquine, lumefantrine thiab mefloquine. Ntau qhov ncauj thiab niam txiv tsim ntawm artemisinin derivatives muaj thoob ntiaj teb. Hauv Tebchaws Meskas, kev sib xyaw ua ke ntawm artemether (20 mg) thiab lumefantrine (120 mg) tau pom zoo rau kev kho tus kab mob P. falciparum malaria xyoo 2009 raws li lub npe Coartem. Cov koob tshuaj pom zoo rau cov neeg laus yog 4 ntsiav tshuaj ob zaug ib hnub rau 3 hnub (6 koob).
Rau ntau Artemisinin, thov hu rau peb ntawm email::herbext@undersun.com.cn
Cov neeg siv: https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC4297758/#: ~: text = 1)., 5 % 2C6 % 2C7 % 5D.
http://www.antimicrobe.org/drugpopup/artemisinin.htm
https://www.healthline.com/health/artemisinin-cancer#side-effects
https://www.ncbi.nlm.nih.gov/books/NBK548419/
